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CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo

BACKGROUND: Chemotherapy in cancer patients can be associated with serious short- and long-term adverse neurological effects, such as leukoencephalopathy and cognitive impairment, even when therapy is delivered systemically. The underlying cellular basis for these adverse effects is poorly understoo...

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Detalhes bibliográficos
Main Authors: Dietrich, Joerg, Han, Ruolan, Yang, Yin, Mayer-Pröschel, Margot, Noble, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000477/
https://ncbi.nlm.nih.gov/pubmed/17125495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/jbiol50
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