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E2F1 Regulates the Base Excision Repair Gene XRCC1 and Promotes DNA Repair

The E2F1 transcription factor activates S-phase-promoting genes, mediates apoptosis, and stimulates DNA repair through incompletely understood mechanisms. XRCC1 (x-ray repair cross-complementing group 1) protein is important for efficient single strand break/base excision repair. Although both damag...

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Библиографические подробности
Главные авторы: Chen, Dexi, Yu, Zhiyong, Zhu, Zhiyi, Lopez, Charles D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397471/
https://ncbi.nlm.nih.gov/pubmed/18348985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710296200
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