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Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain
BACKGROUND: AMP-activated protein kinase (AMPK) is a known physiological cellular energy sensor and becomes phosphorylated at Thr-172 in response to changes in cellular ATP levels. Activated AMPK acts as either an inducer or suppressor of apoptosis depending on the severity of energy stress and the...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2397440/ https://ncbi.nlm.nih.gov/pubmed/18474106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-37 |
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