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Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet

BACKGROUND: Astrocytomas are largely dependent on glycolysis to satisfy their bioenergetic requirements for growth and survival. Therapies that target glycolysis can potentially manage astrocytoma growth and progression. Dietary restriction of the high fat/low carbohydrate ketogenic diet (KD-R) redu...

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Detalhes bibliográficos
Main Authors: Marsh, Jeremy, Mukherjee, Purna, Seyfried, Thomas N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607273/
https://ncbi.nlm.nih.gov/pubmed/19032781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-5-33
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