Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet

BACKGROUND: Astrocytomas are largely dependent on glycolysis to satisfy their bioenergetic requirements for growth and survival. Therapies that target glycolysis can potentially manage astrocytoma growth and progression. Dietary restriction of the high fat/low carbohydrate ketogenic diet (KD-R) redu...

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Bibliographic Details
Main Authors: Marsh, Jeremy, Mukherjee, Purna, Seyfried, Thomas N
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Brief Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607273/
https://ncbi.nlm.nih.gov/pubmed/19032781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-5-33
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