The Mycobacterium tuberculosis Virulence Factor Trehalose Dimycolate Imparts Desiccation Resistance to Model Mycobacterial Membranes

Mycobacteria, including persistent pathogens like Mycobacterium tuberculosis, have an unusual membrane structure in which, outside the plasma membrane, a nonfluid hydrophobic fatty acid layer supports a fluid monolayer rich in glycolipids such as trehalose 6,6′-dimycolate (TDM; cord factor). Given t...

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Detalles Bibliográficos
Autores principales: Harland, Christopher W., Rabuka, David, Bertozzi, Carolyn R., Parthasarathy, Raghuveer
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2008
Materias:
Membranes
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397374/
https://ncbi.nlm.nih.gov/pubmed/18326657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.125542
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