The Mycobacterium tuberculosis Virulence Factor Trehalose Dimycolate Imparts Desiccation Resistance to Model Mycobacterial Membranes

Mycobacteria, including persistent pathogens like Mycobacterium tuberculosis, have an unusual membrane structure in which, outside the plasma membrane, a nonfluid hydrophobic fatty acid layer supports a fluid monolayer rich in glycolipids such as trehalose 6,6′-dimycolate (TDM; cord factor). Given t...

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Autors principals: Harland, Christopher W., Rabuka, David, Bertozzi, Carolyn R., Parthasarathy, Raghuveer
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2008
Matèries:
Membranes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397374/
https://ncbi.nlm.nih.gov/pubmed/18326657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.125542
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