Protein Dynamics and Stability: The Distribution of Atomic Fluctuations in Thermophilic and Mesophilic Dihydrofolate Reductase Derived Using Elastic Incoherent Neutron Scattering

The temperature dependence of the dynamics of mesophilic and thermophilic dihydrofolate reductase is examined using elastic incoherent neutron scattering. It is demonstrated that the distribution of atomic displacement amplitudes can be derived from the elastic scattering data by assuming a (Weibull...

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Bibliografiske detaljer
Main Authors: Meinhold, Lars, Clement, David, Tehei, Moeava, Daniel, Roy, Finney, John L., Smith, Jeremy C.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2008
Fag:
Proteins
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397366/
https://ncbi.nlm.nih.gov/pubmed/18310248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.121418
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