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Observation of Noncooperative Folding Thermodynamics in Simulations of 1BBL

One of the predictions of the energy landscape theory of protein folding is the possibility of barrierless, “downhill” folding under certain conditions. The protein 1BBL has been proposed to fold by such a downhill mechanism, though this is a matter of some dispute. We carried out extensive replica...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pitera, Jed W., Swope, William C., Abraham, Farid F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397362/
https://ncbi.nlm.nih.gov/pubmed/18326644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.123265
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