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Observation of Two Families of Folding Pathways of BBL

BBL is an independent folding domain of a large multienzyme complex, 2-oxoglutarate dehydrogenase. The folding mechanism of BBL is under debate between the views of noncooperative downhill-type and classical two-state. Extensive replica exchange molecular dynamics simulations of BBL in explicit solv...

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Detalhes bibliográficos
Main Authors: Fan, Jue, Duan, Mojie, Li, Da-Wei, Wu, Hao, Yang, Haijun, Han, Li, Huo, Shuanghong
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093567/
https://ncbi.nlm.nih.gov/pubmed/21575580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.03.058
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