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Redundant Roles of BIG2 and BIG1, Guanine-Nucleotide Exchange Factors for ADP-Ribosylation Factors in Membrane Traffic between the trans-Golgi Network and Endosomes

BIG2 and BIG1 are closely related guanine-nucleotide exchange factors (GEFs) for ADP-ribosylation factors (ARFs) and are involved in the regulation of membrane traffic through activating ARFs and recruiting coat protein complexes, such as the COPI complex and the AP-1 clathrin adaptor complex. Altho...

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Autors principals: Ishizaki, Ray, Shin, Hye-Won, Mitsuhashi, Hiroko, Nakayama, Kazuhisa
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397321/
https://ncbi.nlm.nih.gov/pubmed/18417613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-10-1067
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