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Differential Effects of Depletion of ARL1 and ARFRP1 on Membrane Trafficking between the trans-Golgi Network and Endosomes

ARFRP1 and ARL1, which are both ARF-like small GTPases, are mammalian orthologs of yeast Arl3p and Arl1p, respectively. In yeast, Arl3p targeted to trans-Golgi network (TGN) membranes activates Arl1p, and the activated Arl1p in turn recruits a GRIP domain-containing protein; this complex regulates r...

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Main Authors: Nishimoto-Morita, Kirika, Shin, Hye-Won, Mitsuhashi, Hiroko, Kitamura, Masashi, Zhang, Qian, Johannes, Ludger, Nakayama, Kazuhisa
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667745/
https://ncbi.nlm.nih.gov/pubmed/19224922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900847200
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