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Novel Interactions of ESCRT-III with LIP5 and VPS4 and their Implications for ESCRT-III Disassembly

The AAA+ ATPase VPS4 plays an essential role in multivesicular body biogenesis and is thought to act by disassembling ESCRT-III complexes. VPS4 oligomerization and ATPase activity are promoted by binding to LIP5. LIP5 also binds to the ESCRT-III like protein CHMP5/hVps60, but how this affects its fu...

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Hlavní autoři: Shim, Soomin, Merrill, Samuel A., Hanson, Phyllis I.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397308/
https://ncbi.nlm.nih.gov/pubmed/18385515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-12-1263
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