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Claspin Promotes Normal Replication Fork Rates in Human Cells
The S phase-specific adaptor protein Claspin mediates the checkpoint response to replication stress by facilitating phosphorylation of Chk1 by ataxia-telangiectasia and Rad3-related (ATR). Evidence suggests that these components of the ATR pathway also play a critical role during physiological S pha...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Cell Biology
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2397295/ https://ncbi.nlm.nih.gov/pubmed/18353973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-10-1035 |
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