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Claspin Promotes Normal Replication Fork Rates in Human Cells

The S phase-specific adaptor protein Claspin mediates the checkpoint response to replication stress by facilitating phosphorylation of Chk1 by ataxia-telangiectasia and Rad3-related (ATR). Evidence suggests that these components of the ATR pathway also play a critical role during physiological S pha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Petermann, Eva, Helleday, Thomas, Caldecott, Keith W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2397295/
https://ncbi.nlm.nih.gov/pubmed/18353973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-10-1035
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