Production of a novel dimeric metabolite of primaquine by Streptomyces rimosus.

Primaquine, an 8-amino-6-methoxyquinoline antimalarial agent, was subjected to metabolic studies with microorganisms. Streptomyces rimosus converted primaquine to the previously reported N-acetyl derivative. Continued incubation of S. rimosus resulted in the formation of a minor dimeric metabolite....

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Bibliographic Details
Published in:Appl Environ Microbiol
Main Authors: Clark, A M, Hufford, C D, Puri, R K, McChesney, J D
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1984
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239717/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6712222/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.47.3.540-543.1984
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