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Microbial transformation of primaquine by Candida tropicalis.

The microbial metabolism of primaquine, a 6-methoxy-8-aminoquinoline antimalarial agent, was investigated. The yeast Candida tropicalis was found to convert primaquine to the previously reported N-acetylated derivative. On continued incubation of C. tropicalis in the presence of the N-acetylated der...

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Main Authors: Clark, A M, Hufford, C D, Gupta, R C, Puri, R K, McChesney, J D
格式: Artigo
語言:Inglês
出版: 1984
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC239716/
https://ncbi.nlm.nih.gov/pubmed/6712221
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