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Microbial transformation of primaquine by Candida tropicalis.

The microbial metabolism of primaquine, a 6-methoxy-8-aminoquinoline antimalarial agent, was investigated. The yeast Candida tropicalis was found to convert primaquine to the previously reported N-acetylated derivative. On continued incubation of C. tropicalis in the presence of the N-acetylated der...

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Détails bibliographiques
Publié dans:Appl Environ Microbiol
Auteurs principaux: Clark, A M, Hufford, C D, Gupta, R C, Puri, R K, McChesney, J D
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC239716/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6712221/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aem.47.3.537-539.1984
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