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HIV-1 Vif promotes the formation of high molecular mass APOBEC3G complexes

HIV-1 Vif inhibits the antiviral activity of APOBEC3G (APO3G) by inducing proteasomal degradation. Here, we studied the effects of Vif on APO3G in vitro. In this system, Vif did not cause APO3G degradation. Instead, Vif induced changes in APO3G that affected immunoprecipitation of the native protein...

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Autors principals: Goila-Gaur, Ritu, Khan, Mohammad A., Miyagi, Eri, Kao, Sandra, Opi, Sandrine, Takeuchi, Hiroaki, Strebel, Klaus
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396953/
https://ncbi.nlm.nih.gov/pubmed/18023836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2007.10.017
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