Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions

Ras guanine nucleotide exchange factor (GEF) Q, a nucleotide exchange factor from Dictyostelium discoideum, is a 143-kD protein containing RasGEF domains and a DEP domain. We show that RasGEF Q can bind to F-actin, has the potential to form complexes with myosin heavy chain kinase (MHCK) A that cont...

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Autores principales: Mondal, Subhanjan, Bakthavatsalam, Deenadayalan, Steimle, Paul, Gassen, Berthold, Rivero, Francisco, Noegel, Angelika A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2008
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396803/
https://ncbi.nlm.nih.gov/pubmed/18504297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200710111
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