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Omalizumab Reverses the Phenotypic and Functional Effects of IgE-Enhanced FcεRI on Human Skin Mast Cells

The dramatic effects of the anti-IgE mAb omalizumab to lower free IgE levels and FcεRI levels on basophils contrast with more modest clinical effects. Accordingly, whether IgE modulates FcεRI levels and FcεRI-dependent mediator release in vitro on human skin mast cells (MC(TC) type) that had matured...

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Sonraí Bibleagrafaíochta
Main Authors: Gomez, Gregorio, Jogie-Brahim, Sherryline, Shima, Mika, Schwartz, Lawrence B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396781/
https://ncbi.nlm.nih.gov/pubmed/17617628
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