Prostaglandin E(2) suppresses LPS-stimulated IFNβ production

Macrophages activate the production of cytokines and chemokines in response to LPS through signaling cascades downstream from TLR4. Lipid mediators such as PGE(2), which are produced during inflammatory responses, have been shown to suppress MyD88-dependent gene expression upon TLR4 activation in ma...

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Autors principals: Julia Xu, X., Reichner, Jonathan S., Mastrofrancesco, Balduino, Henry, William L., Albina, Jorge E.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396778/
https://ncbi.nlm.nih.gov/pubmed/18250418
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