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Differential Regulation of Pregnancy Associated Plasma Protein-A in Human Coronary Artery Endothelial Cells and Smooth Muscle Cells

BACKGROUND: Pregnancy-associated plasma protein-A (PAPP-A), a metalloproteinase that serves to modulate local insulin-like growth factor (IGF) action, is upregulated in atherosclerotic plaque. However, little is known about the cellular mechanisms underlying this elevated PAPP-A. OBJECTIVE: To conti...

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Detalhes bibliográficos
Main Authors: Conover, Cheryl A., Harrington, Sean C., Bale, Laurie K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396756/
https://ncbi.nlm.nih.gov/pubmed/17936662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2007.09.001
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