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PDGF-C Is a Proinflammatory Cytokine that Mediates Renal Interstitial Fibrosis
PDGF-C is a potent mitogen for fibroblasts in vitro. Transgenic PDGF-C overexpression in the heart or liver induces organ fibrosis, and PDGF-C expression is upregulated at sites of interstitial fibrosis in human and rat kidneys; however, the effect of inhibiting PDGF-C on the development of renal fi...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Nephrology
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396746/ https://ncbi.nlm.nih.gov/pubmed/18184860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007030290 |
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