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Aldosterone-Stimulated SGK1 Activity Mediates Profibrotic Signaling in the Mesangium

Several recent reports support the hypothesis that aldosterone contributes to the progression of renal injury. Mineralocorticoids increase the expression of serum- and glucocorticoid-inducible protein kinase 1 (SGK1), which is upregulated in several fibrotic diseases. It was hypothesized that SGK1 m...

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Detalhes bibliográficos
Main Authors: Terada, Yoshio, Kuwana, Hitoshi, Kobayashi, Takahiko, Okado, Tomokazu, Suzuki, Noriko, Yoshimoto, Takanobu, Hirata, Yukio, Sasaki, Sei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396734/
https://ncbi.nlm.nih.gov/pubmed/18184857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007050531
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