Regulation of tumor necrosis factor receptor-1 and the IKK-NF-κB pathway by LDL receptor–related protein explains the antiinflammatory activity of this receptor

Low-density lipoprotein receptor–related protein (LRP-1) functions in endocytosis and in cell signaling directly (by binding signaling adaptor proteins) or indirectly (by regulating levels of other cell-surface receptors). Because recent studies in rodents suggest that LRP-1 inhibits inflammation, w...

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Detalhes bibliográficos
Main Authors: Gaultier, Alban, Arandjelovic, Sanja, Niessen, Sherry, Overton, Cheryl D., Linton, MacRae F., Fazio, Sergio, Campana, W. Marie, Cravatt, Benjamin F., Gonias, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Hemostasis, Thrombosis, and Vascular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396725/
https://ncbi.nlm.nih.gov/pubmed/18369152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-127613
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