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Neuroprotection via matrix-trophic coupling between cerebral endothelial cells and neurons

The neurovascular unit is an emerging concept that emphasizes homeostatic interactions between endothelium and cerebral parenchyma. Here, we show that cerebral endothelium are not just inert tubes for delivering blood, but they also secrete trophic factors that can be directly neuroprotective. Condi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guo, Shuzhen, Kim, Woo Jean, Lok, Josephine, Lee, Sun-Ryung, Besancon, Elaine, Luo, Bing-Hao, Stins, Monique F., Wang, Xiaoying, Dedhar, Shoukat, Lo, Eng H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396701/
https://ncbi.nlm.nih.gov/pubmed/18495934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801105105
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