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Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1

Luteolin, a flavonoid found in high concentrations in celery and green pepper, has been shown to reduce production of proinflammatory mediators in LPS-stimulated macrophages, fibroblasts, and intestinal epithelial cells. Because excessive production of proinflammatory cytokines by activated brain mi...

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Autori principali: Jang, Saebyeol, Kelley, Keith W., Johnson, Rodney W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396685/
https://ncbi.nlm.nih.gov/pubmed/18490655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0802865105
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