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Intra-endodermal interactions are required for pancreatic β-cell induction

The cellular origin of signals that regulate pancreatic β-cell induction is not clearly defined. Here, we investigate the seeming paradox that Hedgehog/Smoothened signaling functions during gastrulation to promote pancreatic β-cell development in zebrafish, yet has an inhibitory role during later st...

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Autores principales: Chung, Won-Suk, Stainier, Didier Y. R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396532/
https://ncbi.nlm.nih.gov/pubmed/18410733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.02.012
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