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Intra-endodermal interactions are required for pancreatic β-cell induction
The cellular origin of signals that regulate pancreatic β-cell induction is not clearly defined. Here, we investigate the seeming paradox that Hedgehog/Smoothened signaling functions during gastrulation to promote pancreatic β-cell development in zebrafish, yet has an inhibitory role during later st...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396532/ https://ncbi.nlm.nih.gov/pubmed/18410733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.02.012 |
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