Antibody Complementarity-Determining Regions (CDRs) Can Display Differential Antimicrobial, Antiviral and Antitumor Activities

BACKGROUND: Complementarity-determining regions (CDRs) are immunoglobulin (Ig) hypervariable domains that determine specific antibody (Ab) binding. We have shown that synthetic CDR-related peptides and many decapeptides spanning the variable region of a recombinant yeast killer toxin-like antiidioty...

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Detalhes bibliográficos
Main Authors: Polonelli, Luciano, Pontón, José, Elguezabal, Natalia, Moragues, María Dolores, Casoli, Claudio, Pilotti, Elisabetta, Ronzi, Paola, Dobroff, Andrey S., Rodrigues, Elaine G., Juliano, Maria A., Maffei, Domenico Leonardo, Magliani, Walter, Conti, Stefania, Travassos, Luiz R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396520/
https://ncbi.nlm.nih.gov/pubmed/18545659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002371
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