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IRES-Mediated Translation of Utrophin A Is Enhanced by Glucocorticoid Treatment in Skeletal Muscle Cells

Glucocorticoids are currently the only drug treatment recognized to benefit Duchenne muscular dystrophy (DMD) patients. The nature of the mechanisms underlying the beneficial effects remains incompletely understood but may involve an increase in the expression of utrophin. Here, we show that treatme...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Miura, Pedro, Andrews, Meghan, Holcik, Martin, Jasmin, Bernard J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396518/
https://ncbi.nlm.nih.gov/pubmed/18545658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002309
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