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CSMET: Comparative Genomic Motif Detection via Multi-Resolution Phylogenetic Shadowing

Functional turnover of transcription factor binding sites (TFBSs), such as whole-motif loss or gain, are common events during genome evolution. Conventional probabilistic phylogenetic shadowing methods model the evolution of genomes only at nucleotide level, and lack the ability to capture the evolu...

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Detalhes bibliográficos
Main Authors: Ray, Pradipta, Shringarpure, Suyash, Kolar, Mladen, Xing, Eric P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396503/
https://ncbi.nlm.nih.gov/pubmed/18535663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000090
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