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Mismatched dNTP incorporation by DNA polymerase β does not proceed via globally different conformational pathways(†)

Understanding how DNA polymerases control fidelity requires elucidation of the mechanisms of matched and mismatched dNTP incorporations. Little is known about the latter because mismatched complexes do not crystallize readily. In this report, we employed small-angle X-ray scattering (SAXS) and struc...

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Main Authors: Tang, Kuo-Hsiang, Niebuhr, Marc, Tung, Chang-Shung, Chan, Hsiu-chien, Chou, Chia-Cheng, Tsai, Ming-Daw
格式: Artigo
語言:Inglês
出版: Oxford University Press 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396427/
https://ncbi.nlm.nih.gov/pubmed/18385153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn138
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