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Mismatched dNTP incorporation by DNA polymerase β does not proceed via globally different conformational pathways(†)
Understanding how DNA polymerases control fidelity requires elucidation of the mechanisms of matched and mismatched dNTP incorporations. Little is known about the latter because mismatched complexes do not crystallize readily. In this report, we employed small-angle X-ray scattering (SAXS) and struc...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396427/ https://ncbi.nlm.nih.gov/pubmed/18385153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn138 |
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