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Formation of the double helix: a mutational study
To investigate the mechanisms by which oligonucleotides hybridize to target molecules, the binding of two oligodeoxynucleotide probes to RNA targets was measured over a broad range of temperatures. Mutations were then scanned across each DNA/RNA hybrid to map, at single base resolution, sequences im...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396424/ https://ncbi.nlm.nih.gov/pubmed/18388130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn134 |
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