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Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron
RNA interference (RNAi) is a powerful approach to inhibit human immunodeficiency virus type 1 (HIV-1) replication. However, HIV-1 can escape from RNAi-mediated antiviral therapy by selection of mutations in the targeted sequence. To prevent viral escape, multiple small interfering RNAs (siRNAs) agai...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2396423/ https://ncbi.nlm.nih.gov/pubmed/18346971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn109 |
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