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An integrated systems biology approach to understanding the rules of keratinocyte colony formation

Closely coupled in vitro and in virtuo models have been used to explore the self-organization of normal human keratinocytes (NHK). Although it can be observed experimentally, we lack the tools to explore many biological rules that govern NHK self-organization. An agent-based computational model was...

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Main Authors: Sun, Tao, McMinn, Phil, Coakley, Simon, Holcombe, Mike, Smallwood, Rod, MacNeil, Sheila
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396345/
https://ncbi.nlm.nih.gov/pubmed/17374590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2007.0227
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