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An ancient family of human endogenous retroviruses encodes a functional homolog of the HIV-1 Rev protein

The human endogenous retrovirus K (HERV-K) family of endogenous retroviruses consists of ≈50 proviral copies per haploid human genome. Herein, the HERV-Ks are shown to encode a sequence-specific nuclear RNA export factor, termed K-Rev, that is functionally analogous to the HIV-1 Rev protein. Like HI...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Yang, Jin, Bogerd, Hal P., Peng, Sheila, Wiegand, Heather, Truant, Ray, Cullen, Bryan R.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1999
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23960/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10557333/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.23.13404
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