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An ancient family of human endogenous retroviruses encodes a functional homolog of the HIV-1 Rev protein

The human endogenous retrovirus K (HERV-K) family of endogenous retroviruses consists of ≈50 proviral copies per haploid human genome. Herein, the HERV-Ks are shown to encode a sequence-specific nuclear RNA export factor, termed K-Rev, that is functionally analogous to the HIV-1 Rev protein. Like HI...

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Detalhes bibliográficos
Main Authors: Yang, Jin, Bogerd, Hal P., Peng, Sheila, Wiegand, Heather, Truant, Ray, Cullen, Bryan R.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC23960/
https://ncbi.nlm.nih.gov/pubmed/10557333
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