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Attenuation of virulence by P and V plasmids in Vibrio cholerae: strains suitable for oral immunization
In a virulent strain of Vibrio cholerae, KB9, P and V plasmids were introduced by bacterial conjugation. Characterization of PV isolates and systematic screening of them in animal models of cholera revealed that a large number of PV isolates were non-pathogenic, owing to the loss of ability to synth...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1979
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2395831/ https://ncbi.nlm.nih.gov/pubmed/316741 |
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