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Attenuation of virulence by P and V plasmids in Vibrio cholerae: strains suitable for oral immunization

In a virulent strain of Vibrio cholerae, KB9, P and V plasmids were introduced by bacterial conjugation. Characterization of PV isolates and systematic screening of them in animal models of cholera revealed that a large number of PV isolates were non-pathogenic, owing to the loss of ability to synth...

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Библиографические подробности
Главные авторы: Sinha, V. B., Srivastava, Brahm S.
Формат: Artigo
Язык:Inglês
Опубликовано: 1979
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395831/
https://ncbi.nlm.nih.gov/pubmed/316741
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