Persistent Replication of Severe Acute Respiratory Syndrome Coronavirus in Human Tubular Kidney Cells Selects for Adaptive Mutations in the Membrane Protein

Severe acute respiratory syndrome (SARS) is a systemic disease characterized by both lung pathology and widespread extrapulmonary virus dissemination causing multiple organ injuries. In this regard, renal dysfunction is an ominous sign in patients with SARS. Indeed, clusters of SARS coronavirus (SAR...

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Detalhes bibliográficos
Main Authors: Pacciarini, Filippo, Ghezzi, Silvia, Canducci, Filippo, Sims, Amy, Sampaolo, Michela, Ferioli, Elena, Clementi, Massimo, Poli, Guido, Conaldi, Pier Giulio, Baric, Ralph, Vicenzi, Elisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395189/
https://ncbi.nlm.nih.gov/pubmed/18367528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00096-08
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