Persistent Replication of Severe Acute Respiratory Syndrome Coronavirus in Human Tubular Kidney Cells Selects for Adaptive Mutations in the Membrane Protein

Severe acute respiratory syndrome (SARS) is a systemic disease characterized by both lung pathology and widespread extrapulmonary virus dissemination causing multiple organ injuries. In this regard, renal dysfunction is an ominous sign in patients with SARS. Indeed, clusters of SARS coronavirus (SAR...

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Bibliographische Detailangaben
Hauptverfasser: Pacciarini, Filippo, Ghezzi, Silvia, Canducci, Filippo, Sims, Amy, Sampaolo, Michela, Ferioli, Elena, Clementi, Massimo, Poli, Guido, Conaldi, Pier Giulio, Baric, Ralph, Vicenzi, Elisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395189/
https://ncbi.nlm.nih.gov/pubmed/18367528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00096-08
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