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Critical Role of Virion-Associated Cholesterol and Sphingolipid in Hepatitis C Virus Infection

In this study, we establish that cholesterol and sphingolipid associated with hepatitis C virus (HCV) particles are important for virion maturation and infectivity. In a recently developed culture system enabling study of the complete life cycle of HCV, mature virions were enriched with cholesterol...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aizaki, Hideki, Morikawa, Kenichi, Fukasawa, Masayoshi, Hara, Hiromichi, Inoue, Yasushi, Tani, Hideki, Saito, Kyoko, Nishijima, Masahiro, Hanada, Kentaro, Matsuura, Yoshiharu, Lai, Michael M. C., Miyamura, Tatsuo, Wakita, Takaji, Suzuki, Tetsuro
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395132/
https://ncbi.nlm.nih.gov/pubmed/18367533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02530-07
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