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Increased levels of plasma lysosomal enzymes in patients with Lowe syndrome

Lowe syndrome is an X-linked disorder that has a complex phenotype that includes progressive renal failure and blindness. The disease is caused by mutations in an inositol polyphosphate 5-phosphatase designated OCRL. It has been shown that the OCRL protein is found on the surface of lysosomes and th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ungewickell, Alexander J., Majerus, Philip W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC23949/
https://ncbi.nlm.nih.gov/pubmed/10557322
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