Central role of a defective interleukin-2 production in triggering islet autoimmune destruction

The dynamics of CD4(+) effector T (Teff)cells and CD4(+)Foxp3(+) regulatory T (Treg)cells during diabetes progression in non-obese diabetic mice was investigated to determine if an imbalance of Treg cells and Teff cells contributes to the development of type 1 diabetes. Our results demonstrated a pr...

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Detalhes bibliográficos
Main Authors: Tang, Qizhi, Adams, Jason Y., Penaranda, Cristina, Melli, Kristin, Piaggio, Eliane, Sgouroudis, Evridiki, Piccirillo, Ciriaco A., Salomon, Benoit L., Bluestone, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394854/
https://ncbi.nlm.nih.gov/pubmed/18468463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.03.016
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