Wordt geladen...
Tractable Cre-lox system for stochastic alteration of genes in mice
We developed a cell division–activated Cre-lox system for stochastic recombination of loxP-flanked loci in mice. Cre activation by frameshift reversion is modulated by DNA mismatch-repair status and occurs in individual cells surrounded by normal tissue, mimicking spontaneous cancer-causing mutation...
Bewaard in:
| Hoofdauteurs: | , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394730/ https://ncbi.nlm.nih.gov/pubmed/18264106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/NMETH.1183 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|