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Repeated methamphetamine causes long-lasting presynaptic corticostriatal depression that is renormalized with drug readministration

Addiction-associated behaviors such as drug craving and relapse are hypothesized to result from synaptic changes that persist long after withdrawal that are renormalized by drug reinstatement, although such chronic synaptic effects have not been identified. We report that exposure to the dopamine re...

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Detalhes bibliográficos
Main Authors: Bamford, Nigel S., Zhang, Hui, Joyce, John A., Scarlis, Christine A., Hanan, Whitney, Wu, Nan-Ping, André, Véronique M., Cohen, Rachel, Cepeda, Carlos, Levine, Michael S., Harleton, Erin, Sulzer, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394729/
https://ncbi.nlm.nih.gov/pubmed/18400166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.01.033
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