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REM sleep changes in rats induced by siRNA-mediated orexin knockdown
Short interfering RNAs (siRNA) targeting prepro-orexin mRNA were microinjected into the rat perifornical hypothalamus. Prepro-orexin siRNA-treated rats had a significant (59%) reduction in prepro-orexin mRNA compared to scrambled siRNA-treated rats 2 days postinjection, whereas prodynorphin mRNA was...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2394504/ https://ncbi.nlm.nih.gov/pubmed/17067300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2006.05058.x |
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