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Knockdown of orexin type 2 receptor in the lateral pontomesencephalic tegmentum of rats increases REM sleep

Dysfunction of the orexin/hypocretin neurotransmitter system causes the sleep disorder narcolepsy, characterized by intrusion of rapid-eye-movement (REM) sleep-like events into normal wakefulness. The sites where orexins act to suppress REM sleep are incompletely understood. Previous studies suggest...

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Detalhes bibliográficos
Main Authors: Chen, Lichao, McKenna, James T., Bolortuya, Yunren, Brown, Ritchie E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3604039/
https://ncbi.nlm.nih.gov/pubmed/23282008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12101
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