Potentiation of ionising radiation by targeting tumour necrosis factor alpha using a bispecific antibody in human pancreatic cancer

The aim of this study was to treat carcinoembryonic antigen (CEA)-expressing pancreatic carcinoma cells with tumour necrosis factor alpha (TNFα) and simultaneous radiation therapy (RT), using a bispecific antibody (BAb) anti-TNFα/anti-CEA. TNFα used alone produced a dose-dependent inhibition of the...

Full description

Saved in:
Bibliographic Details
Main Authors: Azria, D, Larbouret, C, Garambois, V, Kramar, A, Martineau, P, Robert, B, Aillères, N, Ychou, M, Dubois, J B, Pèlegrin, A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2003
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2394444/
https://ncbi.nlm.nih.gov/pubmed/14612914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601362
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items